Analisis Tingkat Pemberian Tindakan Trombolisis pada Pasien Stroke Iskemik di RSUD Sleman

Abstract

Background: Ischemic stroke is a leading cause of death and disability worldwide. Although thrombolysis is effective in improving neurological function, its administration rate remains low in Southeast Asia, including Indonesia. RSUD Sleman, as a referral hospital for stroke in Yogyakarta, has adequate facilities, but the percentage of thrombolysis administration remains unclear. Therefore, this study is important to determine the extent to which thrombolytic therapy has been implemented. Objective: To determine the rate of thrombolytic administration in ischemic stroke patients at RSUD Sleman and analyze the influencing factors. Methods: This research employed a cross-sectional design with retrospective data collected from medical records of ischemic stroke patients treated at RSUD Sleman in 2024. The data included demographic characteristics, clinical progression, and medication use. Descriptive and inferential analyses were conducted using logistic regression. Results: Only 6.55% of 458 ischemic stroke patients received thrombolytic therapy. Most patients arrived beyond the golden period (4.5 hours). Bivariate analysis showed a significant association between arrival time and stroke history with thrombolytic administration. However, multivariate analysis found no factors significantly associated. Conclusion: The low rate of thrombolysis administration at RSUD Sleman is likely associated with delayed patient arrival due to a lack of awareness of stroke symptoms, highlighting the need for further assessment of both public knowledge and healthcare provider-related aspects.