| dc.description.abstract | Background: Melasma is a symmetrical hyperpigmentation on the face that
affects the dermis and epidermis. There are three clinical features of melasma,
namely centrofacial, malar and mandibular. In general, mechanism of melasma
treatment is to inhibit pigment production and inhibit the transfer of melanosomes
to keratinocytes. Until now there is still no melasma treatment that fully satisfies
both patients and clinicians. This review aims to collect the clinical features and
management of melasma
Method: TThe data for this review were obtained through databases like PubMed,
Sciencedirect, EBSCOhost, National Library of Indonesia e-Journal, and Google
Scholar. The journal publication year is limited to at least 2017. The keywords
used in the search are (“Melasma” OR “Chloasma Faciei”) AND (“Treatment” OR
“Management”). The inclusion criteria used are articles or journals covering
clinical types of melasma and their management, research published in 2017 -
2023, articles are original articles, journals are written in English or Indonesian,
research subjects are humans, there are clinical types of melasma in subject
characteristics, and research using MASI as parameter. Article extraction is using
PRISMA-ScR algorithm.
Results : Nine articles containing clinical descriptions of melasma, management
of melasma, results of melasma treatment, and side effects of treatment were
extracted. The most common clinical presentation of melasma is malar followed
by centrofacial and mandibular. Treatment can be carried out with
pharmacological, non-pharmacological, and combination treatments. Almost all
melasma treatments still have side effects and high recurrence rates.
Conclusions: The most common clinical feature of melasma is malar melasma.
There are many types of melasma treatments but until now there has been no
satisfactory treatment. | en_US |
