| dc.description.abstract | In 2019, AMR was responsible for 4.95 million mortality, more than HIV/AIDS and malaria combined. Researchers predict an increase in global antibiotic consumption of up to 200% by 2030 if there are no changes in implementation. Access, Watch, and Reserve (AWaRe) antibiotics classification was released in 2019 by the World Health Organization (WHO), and the Ministry of Health of the Republic of Indonesia (MoHRI) released the same classification in 2021 for use nationally in Indonesia. The classification's primary objective is to facilitate the implementation of antimicrobial stewardship programs in all healthcare facilities. WHO encourages global action to improve the availability of antibiotics in the Access group by over 60% with the goal of stopping the progression of antimicrobial resistance. One of the important activities to optimize the use of antibiotics is ongoing evaluation both quantitatively and qualitatively. The main objective of this research is to determine the profile of antibiotic use at M. Yunus Hospital Bengkulu during the 2018-2022 period based on the AwaRe (Access, Watch and Reserve) classification from the World Health Organization (WHO) and the Ministry of Health of the Republic of Indonesia (Kemenkes RI). This research uses secondary data on antibiotic consumption collected from the M. Yunus Hospital Information System, Bengkulu Province during the 2018-2022 period. Data processing in this research was carried out quantitatively using the ATC/DDD (Anatomical Therapeutic Chemical/Defined Daily Dose) method. Antibiotic consumption is expressed in units of DDD/1000 patient-days for outpatients and DDD/100 patient-days for inpatients. This study found that Watch class antibiotics dominate the drug use segment at 90% (DU 90%) of antibiotics in outpatients and inpatients. The Watch group antibiotic agents used highest for outpatients were Cefixime and Azithromycin. Ceftriaxone and Cefixime were the antibiotic agents with the highest use for inpatients during the study period. The trendline results show a decrease in the use of the Access group and an increase in the use of the Watch group during the research period, both according to the AWaRe Classification from WHO and from the Indonesian Ministry of Health. This research concludes that it is necessary to optimize the role of the team implementing the antimicrobial resistance control program at M. Yunus Hospital Bengkulu
by implementing a pre-authorization system for the use of AWaRe Classified antibiotics
so that global goals can be achieved. | en_US |
