| dc.description.abstract | Jatropha multifida Linn. is an ornamental plant that has a strong
antibacterial benefit. Some of the world's population has been applying this plant
as antibacterial for some infection diseases. The purpose of this research was to
develop the potential of the compounds that contained in Jatropha multifida Linn.
maximally becomes a drug that utilized by the community. Extract of ethyl acetate
stem of Jatropha multifida Linn. as much as 25 mg is inserted into the polymer
ratio HPMC K15 : PVP (1:2) as a patch formula which will be test against
Staphylococcus aureus and Methicillin-Resistant Staphylococcus aureus bacteria
to determine the ability of patch in inhibiting bacterial growth. Results of the test
include the physical character of patch resulting transparent form, flat surface,
non-bubbly, typical smell, and slightly oily. The average measurement of total
flavonoid content was 430,820±42,79 μg RE / g patch and the mean total phenol
content was 487,244±40,65 μg GAE / g patch. The result of effectiveness test
showed that the obstacles zone formed are inhibiting bacteria growth with the
average obstacles zone in the test against Staphylococcus aureus bacteria 105
CFU/ml is 11.7 mm and on the test against Methicillin-Resistant Staphylococcus
aureus 105 CFU/ml is 11 mm. | en_US |
