dc.description.abstract | Backgrounds: Clozapine is one of second generation antipsychotic which is
given to unrespossive schizophrenic patient. Clozapine’s effect on hematologic
especially hemoglobin level has not been studied much. Clozapine is rare to
given alone and often combined with haloperidol. Objective:To know the
diference of hemoglobin level before and after long term treatment of clozapine
and haloperidol in combination. Methods:Information on age, sex, medical
comorbidities, and complete blood counts were collected from medical records of
72 patients from Grhasia Hospital that have been treated with combined treatment
of clozapine and haloperidol more than six months. Data were analyzed with
paired t test.Results: The average of hemoglobin level before treatment
was14,558 ± 1,60 g/dL and the average after treatment was 13,744 ± 1,66
g/dLThe result from paired t test shown that p=0,000. Conclusions:There was
significant differences of hemoglobin level before and after treatment (p=0,000). | en_US |