dc.contributor.author | Lestariana, Wiryatun | |
dc.contributor.author | Ali Akhmad, Syaefudin | |
dc.date.accessioned | 2017-08-26T03:04:15Z | |
dc.date.available | 2017-08-26T03:04:15Z | |
dc.date.issued | 2013-11-04 | |
dc.identifier.issn | 0857-1074 | |
dc.identifier.uri | https://dspace.uii.ac.id/handle/123456789/3567 | |
dc.description | Collections > Lecturers > Faculty of medicine > poster, presentation | en_US |
dc.description.sponsorship | Intoduction
This research is motivated by the many cases of type 2 diabetes every year in posrmenopuasal women. It is thought to be related to decrease levels of estrogen in postmenopausal women because. estrogen plays an important role in the pathogenesis of type 2 diabetes mellitus. Estrogen effects on glucose metabolism are mediated by estrogen receptors alpha (ESR a) in cells. ESR a receptor has been determined by ESR a gene with p and x polymorphi:;;n that can participate in the pathogenesis of type 2 diabetes mellitus. T (p) and A (x) allele of polymorphisma of ESR a have associated with increased risk of osteoporosis, infarction, reduce osteoarthritis, hysterectomy, low BMI, age of menopause and lower risk of type 2 diabetes. So, it needs a new breakthrough in the treatment of type 2 diabetes based on a polymorphism ESR genes. | en_US |
dc.language.iso | en | en_US |
dc.publisher | Journal of the ASEAN Fedaration of Endocrine Societies | en_US |
dc.subject | DIABETES MELLITUS, ESR, POLYMORPHISM | en_US |
dc.title | THERAPY MODELS FOR TYPE 2 DIABETES MELLITUS BASED ON ESR A POLYMORPHISM IN JAVANESE POSTMENOPAUSAL WOMEN INDONESIA | en_US |
dc.type | Presentation | en_US |