Okra (Abelmoschus esculentus L Moench) as Anti-Cholesterolemia, Anti-Diabetic and Anti-Obesity in White Male Rats

Abstract

Hypercholesterolemia is a cholesterol elevation condition in blood serum. Type 2 Diabetes Mellitus is a metabolic disorder which increases significantly in the whole world, associated with obesity and lipid accumulation in the body. Abelmoschus esculentus L Moench is used as an anti-obesity and hypercholesterolemia empirically.The objective of the study is to determine the anti-obesity anti-diabetic and anti-hypercholesterolemia effect of Abelmoschus esculentus L Moench ethanolic extract in animal high-fat diet model. We were conduct shortterm and long-term test. The Blood sample was collected from all rats after 8 hours fasting previously. In short-term (p = 0.000) and long-term test (p = 0.005) showed significantly different between the negative and positive group. Dose III showed no significantly different than positive group (p>0.05) in the short-term test. While, Dose I, II and III showed no significantly different than the positive group to decrease triglyceride level in the long-term test. Dose III showed the best effect to decrease triglyceride level in blood serum and equivalent to the positive group.